Risk Factor as a Central Concept in CARRE

Cardiorenal disease and comorbidities is a complex domain. Related conditions do not have a single cause, but evidence suggests that there are multiple causal chains. In order to capture this in CARRE, current evidence will be presented as a complex network of risk factors, that is, pairs of conditions one related to another via a…

An Overview of the CARRE Medical Domain

CARRE will address the specific medical domain of cardiorenal disease and comorbidities as this is a very common, life threatening and costly condition and because it also presents a number of challenges and opportunities for the demonstration of CARRE outcomes. Cardiorenal syndrome (CRS) is the condition characterised by simultaneous kidney and heart failure while the…